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MAGI1 Prevents Senescence and Promotes the DNA Damage Response in ER(+) Breast Cancer
MAGI1 acts as a tumor suppressor in estrogen receptor-positive (ER(+)) breast cancer (BC), and its loss correlates with a more aggressive phenotype. To identify the pathways and events affected by MAGI1 loss, we deleted the MAGI1 gene in the ER(+) MCF7 BC cell line and performed RNA sequencing and f...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417439/ https://www.ncbi.nlm.nih.gov/pubmed/37566008 http://dx.doi.org/10.3390/cells12151929 |