Cordycepin (3′dA) Induces Cell Death of AC133(+) Leukemia Cells via Re-Expression of WIF1 and Down-Modulation of MYC

SIMPLE SUMMARY: Cordycepin, an analog of adenosine, has shown anti-leukemic properties towards leukemic stem cells (LSCs) by perturbing the leukemia−stroma association. However, the full molecular picture has not been fully elucidated. In addition, Wnt/β-catenin signaling is required for LSC develop...

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Detalles Bibliográficos
Autores principales: Abazari, Nazanin, Stefanucci, Marta Rachele, Bossi, Luca Emanuele, Trojani, Alessandra, Cairoli, Roberto, Beghini, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417454/
https://www.ncbi.nlm.nih.gov/pubmed/37568748
http://dx.doi.org/10.3390/cancers15153931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417454/
https://www.ncbi.nlm.nih.gov/pubmed/37568748
http://dx.doi.org/10.3390/cancers15153931

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