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Cordycepin (3′dA) Induces Cell Death of AC133(+) Leukemia Cells via Re-Expression of WIF1 and Down-Modulation of MYC
SIMPLE SUMMARY: Cordycepin, an analog of adenosine, has shown anti-leukemic properties towards leukemic stem cells (LSCs) by perturbing the leukemia−stroma association. However, the full molecular picture has not been fully elucidated. In addition, Wnt/β-catenin signaling is required for LSC develop...
Autores principales: | Abazari, Nazanin, Stefanucci, Marta Rachele, Bossi, Luca Emanuele, Trojani, Alessandra, Cairoli, Roberto, Beghini, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417454/ https://www.ncbi.nlm.nih.gov/pubmed/37568748 http://dx.doi.org/10.3390/cancers15153931 |
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