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An inducible model of chronic hyperglycemia

Transgene driven expression of Escherichia coli nitroreductase (NTR1.0) renders animal cells susceptible to the antibiotic metronidazole (MTZ). Many NTR1.0/MTZ ablation tools have been reported in zebrafish, which have significantly impacted regeneration studies. However, NTR1.0-based tools are not...

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Detalles Bibliográficos
Autores principales: Tucker, Tori R., Knitter, Courtney A., Khoury, Deena M., Eshghi, Sheida, Tran, Sophia, Sharrock, Abigail V., Wiles, Travis J., Ackerley, David F., Mumm, Jeff S., Parsons, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417516/
https://www.ncbi.nlm.nih.gov/pubmed/37401381
http://dx.doi.org/10.1242/dmm.050215