RXR Agonists Enhance Lenalidomide Anti-Myeloma Activity and T Cell Functions while Retaining Glucose-Lowering Effect

Retinoid X receptor (RXR) heterodimerizes with the PPAR nuclear hormone receptor and regulates its downstream events. We investigated the effects of RXR agonists (LG100754, bexarotene, AGN194204, and LG101506) on lenalidomide’s anti-myeloma activity, T cell functions, and the level of glucose and li...

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Detalles Bibliográficos
Autores principales: Wu, Jian, Wang, Xiaobei, Zhang, Min, Mathews, Parker, Kang, Yubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417536/
https://www.ncbi.nlm.nih.gov/pubmed/37566072
http://dx.doi.org/10.3390/cells12151993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417536/
https://www.ncbi.nlm.nih.gov/pubmed/37566072
http://dx.doi.org/10.3390/cells12151993

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