Cargando…
RXR Agonists Enhance Lenalidomide Anti-Myeloma Activity and T Cell Functions while Retaining Glucose-Lowering Effect
Retinoid X receptor (RXR) heterodimerizes with the PPAR nuclear hormone receptor and regulates its downstream events. We investigated the effects of RXR agonists (LG100754, bexarotene, AGN194204, and LG101506) on lenalidomide’s anti-myeloma activity, T cell functions, and the level of glucose and li...
Autores principales: | Wu, Jian, Wang, Xiaobei, Zhang, Min, Mathews, Parker, Kang, Yubin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417536/ https://www.ncbi.nlm.nih.gov/pubmed/37566072 http://dx.doi.org/10.3390/cells12151993 |
Ejemplares similares
-
SUMOylation inhibition enhances multiple myeloma sensitivity to lenalidomide
por: Du, Li, et al.
Publicado: (2022) -
Lenalidomide versus lenalidomide + dexamethasone prolonged treatment after second‐line lenalidomide + dexamethasone induction in multiple myeloma
por: Lund, Johan, et al.
Publicado: (2018) -
Effects of RXR Agonists on Cell Proliferation/Apoptosis and ACTH Secretion/Pomc Expression
por: Saito-Hakoda, Akiko, et al.
Publicado: (2015) -
RAR/RXR and PPAR/RXR Signaling in Spinal Cord Injury
por: van Neerven, Sabien, et al.
Publicado: (2007) -
Ligand Dependent Switch from RXR Homo- to RXR-NURR1
Heterodimerization
por: Scheepstra, Marcel, et al.
Publicado: (2017)