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The Multikinase Inhibitor AD80 Induces Mitotic Catastrophe and Autophagy in Pancreatic Cancer Cells

SIMPLE SUMMARY: Pancreatic cancer is one of the most lethal human neoplasms, and its therapeutic repertoire remains limited. Advances in understanding the molecular complexity involved in the biology of the disease have paved the way for new therapeutic opportunities. AD80 is a multikinase inhibitor...

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Detalles Bibliográficos
Autores principales: Lima, Keli, de Miranda, Lívia Bassani Lins, Del Milagro Bernabe Garnique, Anali, de Almeida, Bruna Oliveira, do Nascimento, Mariane Cristina, Alcântara, Guilherme Augusto Sousa, Machado-Santelli, Glaucia Maria, Rego, Eduardo Magalhães, Machado-Neto, João Agostinho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417629/
https://www.ncbi.nlm.nih.gov/pubmed/37568682
http://dx.doi.org/10.3390/cancers15153866