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Human Macrophages Polarized by Interaction with Apoptotic Cells Produce Fibrosis-Associated Mediators and Enhance Pro-Fibrotic Activity of Dermal Fibroblasts In Vitro

Apoptosis and subsequent removal of dead cells are an essential part of wound healing. Macrophages phagocytize apoptotic cells (efferocytosis) and contribute to the resolution of inflammation. However, their participation in fibrogenesis and the mechanisms of influence on this process remain unclear...

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Detalles Bibliográficos
Autores principales: Maksimova, Aleksandra, Shevela, Ekaterina, Sakhno, Lyudmila, Tikhonova, Marina, Ostanin, Aleksandr, Chernykh, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417661/
https://www.ncbi.nlm.nih.gov/pubmed/37566007
http://dx.doi.org/10.3390/cells12151928