Neoadjuvant Immunotherapy for Patients with dMMR/MSI-High Gastrointestinal Cancers: A Changing Paradigm

SIMPLE SUMMARY: Immune checkpoint inhibitors (ICIs) have transformed the treatment of mismatch repair-deficient (MMR-D)/microsatellite instability-high (MSI-H) colorectal cancers. These cancers have a high mutation burden and generate antigens called mutation-associated neoantigens (MANAs). ICIs act...

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Detalles Bibliográficos
Autores principales: Ozer, Muhammet, Vegivinti, Charan Thej Reddy, Syed, Masood, Ferrell, Morgan E., Gonzalez Gomez, Cyndi, Cheng, Svea, Holder-Murray, Jennifer, Bruno, Tullia, Saeed, Anwaar, Sahin, Ibrahim Halil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417711/
https://www.ncbi.nlm.nih.gov/pubmed/37568648
http://dx.doi.org/10.3390/cancers15153833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417711/
https://www.ncbi.nlm.nih.gov/pubmed/37568648
http://dx.doi.org/10.3390/cancers15153833

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