Cannabidiol Enhances Cabozantinib-Induced Apoptotic Cell Death via Phosphorylation of p53 Regulated by ER Stress in Hepatocellular Carcinoma

SIMPLE SUMMARY: This study provides evidence that cabozantinib and CBD combination treatment leads to increased apoptosis in HCC cells. We propose that this enhanced apoptosis is mediated, at least in part, through the induction of ER stress and subsequent activation of the p53 pathway. However, our...

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Detalles Bibliográficos
Autores principales: Jeon, Youngsic, Kim, Taejung, Kwon, Hyukjoon, Kim, Jeong-Kook, Park, Young-Tae, Ham, Jungyeob, Kim, Young-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417827/
https://www.ncbi.nlm.nih.gov/pubmed/37568803
http://dx.doi.org/10.3390/cancers15153987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417827/
https://www.ncbi.nlm.nih.gov/pubmed/37568803
http://dx.doi.org/10.3390/cancers15153987

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