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Cannabidiol Enhances Cabozantinib-Induced Apoptotic Cell Death via Phosphorylation of p53 Regulated by ER Stress in Hepatocellular Carcinoma
SIMPLE SUMMARY: This study provides evidence that cabozantinib and CBD combination treatment leads to increased apoptosis in HCC cells. We propose that this enhanced apoptosis is mediated, at least in part, through the induction of ER stress and subsequent activation of the p53 pathway. However, our...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417827/ https://www.ncbi.nlm.nih.gov/pubmed/37568803 http://dx.doi.org/10.3390/cancers15153987 |