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CCT and Cullin1 regulate the TORC1 pathway to promote dendritic arborization in health and disease

The development of cell-type-specific dendritic arbors is integral to the proper functioning of neurons within their circuit networks. In this study, we examine the regulatory relationship between the cytosolic chaperonin CCT, key insulin pathway genes, and an E3 ubiquitin ligase (Cullin1) in homeos...

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Detalles Bibliográficos
Autores principales: Lottes, Erin N., Ciger, Feyza H., Bhattacharjee, Shatabdi, Timmins-Wilde, Emily A., Tete, Benoit, Tran, Tommy, Matta, Jais, Patel, Atit A., Cox, Daniel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418059/
https://www.ncbi.nlm.nih.gov/pubmed/37577581
http://dx.doi.org/10.1101/2023.07.31.551324