Leucine suppresses glucagon secretion from pancreatic islets by directly modulating α-cell cAMP

OBJECTIVE: Pancreatic islets are nutrient sensors that regulate organismal blood glucose homeostasis. Glucagon release from the pancreatic α-cell is important under fasted, fed, and hypoglycemic conditions, yet metabolic regulation of α-cells remains poorly understood. Here, we identified a previous...

Descripción completa

Detalles Bibliográficos
Autores principales: Knuth, Emily R., Foster, Hannah R., Jin, Erli, Merrins, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418066/
https://www.ncbi.nlm.nih.gov/pubmed/37577685
http://dx.doi.org/10.1101/2023.07.31.551113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418066/
https://www.ncbi.nlm.nih.gov/pubmed/37577685
http://dx.doi.org/10.1101/2023.07.31.551113

Ejemplares similares