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Biophysical principles predict fitness of SARS-CoV-2 variants
SARS-CoV-2 employs its spike protein’s receptor binding domain (RBD) to enter host cells. The RBD is constantly subjected to immune responses, while requiring efficient binding to host cell receptors for successful infection. However, understanding how RBD’s biophysical properties contribute to SARS...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418099/ https://www.ncbi.nlm.nih.gov/pubmed/37577536 http://dx.doi.org/10.1101/2023.07.23.549087 |