Cargando…
Biophysical principles predict fitness of SARS-CoV-2 variants
SARS-CoV-2 employs its spike protein’s receptor binding domain (RBD) to enter host cells. The RBD is constantly subjected to immune responses, while requiring efficient binding to host cell receptors for successful infection. However, understanding how RBD’s biophysical properties contribute to SARS...
Autores principales: | Wang, Dianzhuo, Huot, Marian, Mohanty, Vaibhav, Shakhnovich, Eugene I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418099/ https://www.ncbi.nlm.nih.gov/pubmed/37577536 http://dx.doi.org/10.1101/2023.07.23.549087 |
Ejemplares similares
-
Biophysical Fitness Landscape of the SARS-CoV-2 Delta Variant Receptor Binding Domain
por: Patrick, Casey, et al.
Publicado: (2022) -
Online biophysical predictions for SARS-CoV-2 proteins
por: Kagami, Luciano, et al.
Publicado: (2021) -
Biophysical and Biochemical Characterization of the Receptor Binding Domain of SARS-CoV-2 Variants
por: Khatri, Ritika, et al.
Publicado: (2022) -
Prediction and Evolution of the Molecular Fitness of SARS-CoV-2 Variants: Introducing SpikePro
por: Pucci, Fabrizio, et al.
Publicado: (2021) -
Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta
por: Ulrich, Lorenz, et al.
Publicado: (2021)