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Major data analysis errors invalidate cancer microbiome findings

We re-analyzed the data from a recent large-scale study that reported strong correlations between microbial organisms and 33 different cancer types, and that created machine learning predictors with near-perfect accuracy at distinguishing among cancers. We found at least two fundamental flaws in the...

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Detalles Bibliográficos
Autores principales: Gihawi, Abraham, Ge, Yuchen, Lu, Jennifer, Puiu, Daniela, Xu, Amanda, Cooper, Colin S., Brewer, Daniel S., Pertea, Mihaela, Salzberg, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418105/
https://www.ncbi.nlm.nih.gov/pubmed/37577699
http://dx.doi.org/10.1101/2023.07.28.550993