Reactive nitrogen species inhibit branched chain alpha-ketoacid dehydrogenase complex and impact muscle cell metabolism

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Branched chain α-ketoacid dehydrogenase complex (BCKDC) is the rate limiting enzyme in branched chain amino acid (BCAA) catabolism, a metabolic pathway with great importance for human health. BCKDC belongs to the mitochondrial α-ketoacid dehydrogenase complex family, which also includes pyruvate deh...

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Detalles Bibliográficos
Autores principales: Arp, Nicholas L., Seim, Gretchen, Josephson, Jordyn, Fan, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418113/
https://www.ncbi.nlm.nih.gov/pubmed/37577551
http://dx.doi.org/10.1101/2023.07.31.551364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418113/
https://www.ncbi.nlm.nih.gov/pubmed/37577551
http://dx.doi.org/10.1101/2023.07.31.551364

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