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Reactive nitrogen species inhibit branched chain alpha-ketoacid dehydrogenase complex and impact muscle cell metabolism

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Branched chain α-ketoacid dehydrogenase complex (BCKDC) is the rate limiting enzyme in branched chain amino acid (BCAA) catabolism, a metabolic pathway with great importance for human health. BCKDC belongs to the mitochondrial α-ketoacid dehydrogenase complex family, which also includes pyruvate deh...

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Detalles Bibliográficos
Autores principales:	Arp, Nicholas L., Seim, Gretchen, Josephson, Jordyn, Fan, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418113/ https://www.ncbi.nlm.nih.gov/pubmed/37577551 http://dx.doi.org/10.1101/2023.07.31.551364

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