Mechanism of Phosphate Release from Actin Filaments

After ATP-actin monomers assemble filaments, the [Formula: see text]-phosphate is hydrolyzed from ATP within seconds and dissociates from the filament over several minutes. We used all-atom 2-dimensional well-tempered metadynamics computer simulations to sample the release of phosphate from filament...

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Detalles Bibliográficos
Autores principales: Wang, Yihang, Zsolnay, Vilmos, Pollard, Thomas D., Voth, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418243/
https://www.ncbi.nlm.nih.gov/pubmed/37577500
http://dx.doi.org/10.1101/2023.08.03.551904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418243/
https://www.ncbi.nlm.nih.gov/pubmed/37577500
http://dx.doi.org/10.1101/2023.08.03.551904

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