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Mechanism of Phosphate Release from Actin Filaments
After ATP-actin monomers assemble filaments, the [Formula: see text]-phosphate is hydrolyzed from ATP within seconds and dissociates from the filament over several minutes. We used all-atom 2-dimensional well-tempered metadynamics computer simulations to sample the release of phosphate from filament...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418243/ https://www.ncbi.nlm.nih.gov/pubmed/37577500 http://dx.doi.org/10.1101/2023.08.03.551904 |