Modeling Allosteric Mechanisms of Eukaryotic Type II Topoisomerases

Type II topoisomerases (TopoIIs) are essential enzymes involved in critical nuclear processes such as genome organization, chromosome segregation, and various DNA metabolic events. As large, homodimeric complexes, they undergo a complex ATPase cycle that regulates capturing and passing one DNA doubl...

Descripción completa

Detalles Bibliográficos
Autores principales: Evoli, Stefania, Kariyawasam, Nilusha L., Nitiss, Karin C., Nitiss, John L., Wereszczynski, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418245/
https://www.ncbi.nlm.nih.gov/pubmed/37577673
http://dx.doi.org/10.1101/2023.08.02.551689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418245/
https://www.ncbi.nlm.nih.gov/pubmed/37577673
http://dx.doi.org/10.1101/2023.08.02.551689

Ejemplares similares