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Modeling Allosteric Mechanisms of Eukaryotic Type II Topoisomerases
Type II topoisomerases (TopoIIs) are essential enzymes involved in critical nuclear processes such as genome organization, chromosome segregation, and various DNA metabolic events. As large, homodimeric complexes, they undergo a complex ATPase cycle that regulates capturing and passing one DNA doubl...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418245/ https://www.ncbi.nlm.nih.gov/pubmed/37577673 http://dx.doi.org/10.1101/2023.08.02.551689 |