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Identification of factors that prevent ribosome stalling during early elongation

Protein synthesis is catalyzed by the ribosome and a host of highly conserved elongation factors. Most elongation factors that are conserved in all domains of life are essential, such as EF-Tu (e/aEF1A) and EF-G (e/aEF2). In contrast, the universally conserved elongation factor P (EF-P/eIF5A) is ess...

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Detalles Bibliográficos
Autores principales: Hye-Rim, Hong, Prince, Cassidy R., Wu, Letian, Feaga, Heather A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418254/
https://www.ncbi.nlm.nih.gov/pubmed/37577462
http://dx.doi.org/10.1101/2023.08.04.552005