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Multimodal Molecular Imaging Reveals Tissue-Based T Cell Activation and Viral RNA Persistence for Up to 2 Years Following COVID-19

The etiologic mechanisms of post-acute medical morbidities and unexplained symptoms (Long COVID) following SARS-CoV-2 infection are incompletely understood. There is growing evidence that viral persistence and immune dysregulation may play a major role. We performed whole-body positron emission tomo...

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Detalles Bibliográficos
Autores principales: Peluso, Michael J., Ryder, Dylan, Flavell, Robert, Wang, Yingbing, Levi, Jelena, LaFranchi, Brian H., Deveau, Tyler-Marie, Buck, Amanda M., Munter, Sadie E., Asare, Kofi A., Aslam, Maya, Koch, Wally, Szabo, Gyula, Hoh, Rebecca, Deswal, Monika, Rodriguez, Antonio, Buitrago, Melissa, Tai, Viva, Shrestha, Uttam, Lu, Scott, Goldberg, Sarah A., Dalhuisen, Thomas, Durstenfeld, Matthew S., Hsue, Priscilla Y., Kelly, J. Daniel, Kumar, Nitasha, Martin, Jeffrey N., Gambir, Aruna, Somsouk, Ma, Seo, Youngho, Deeks, Steven G., Laszik, Zoltan G., VanBrocklin, Henry F., Henrich, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418298/
https://www.ncbi.nlm.nih.gov/pubmed/37577714
http://dx.doi.org/10.1101/2023.07.27.23293177