Mixed-Lineage Leukemia 1 Inhibition Enhances the Differentiation Potential of Bovine Embryonic Stem Cells by Increasing H3K4 Mono-Methylation at Active Promoters

Mixed-lineage leukemia 1 (MLL1) introduces 1-, 2- and 3-methylation into histone H3K4 through the evolutionarily conserved set domain. In this study, bovine embryonic stem cells (bESCs, known as bESCs-F7) were established from in vitro-fertilized (IVF) embryos via Wnt signaling inhibition; however,...

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Detalles Bibliográficos
Autores principales: Li, Chen, Han, Xuejie, Wang, Jing, Liu, Fang, Zhang, Yuanyuan, Li, Zihong, Lu, Zhenyu, Yue, Yongli, Xiang, Jinzhu, Li, Xueling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418322/
https://www.ncbi.nlm.nih.gov/pubmed/37569280
http://dx.doi.org/10.3390/ijms241511901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418322/
https://www.ncbi.nlm.nih.gov/pubmed/37569280
http://dx.doi.org/10.3390/ijms241511901

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