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The Role of Intracellular Ca(2+) and Mitochondrial ROS in Small Aβ(1-42) Oligomer-Induced Microglial Death

Alzheimer’s disease (AD) is the most common form of dementia worldwide, and it contributes up to 70% of cases. AD pathology involves abnormal amyloid beta (Aβ) accumulation, and the link between the Aβ(1-42) structure and toxicity is of major interest. NMDA receptors (NMDAR) are thought to be essent...

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Detalles Bibliográficos
Autores principales: Jekabsone, Aiste, Jankeviciute, Silvija, Pampuscenko, Katryna, Borutaite, Vilmante, Morkuniene, Ramune
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418347/
https://www.ncbi.nlm.nih.gov/pubmed/37569690
http://dx.doi.org/10.3390/ijms241512315