Fighting Celiac Disease: Improvement of pH Stability of Cathepsin L In Vitro by Computational Design

Roughly 1% of the global population is susceptible to celiac disease (CD)—inheritable autoimmune inflammation of the small intestine caused by intolerance to gliadin proteins present in wheat, rye, and barley grains, and called gluten in wheat. Classical treatment is a life-long gluten-free diet, wh...

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Detalles Bibliográficos
Autores principales: Chugunov, Anton O., Dvoryakova, Elena A., Dyuzheva, Maria A., Simonyan, Tatyana R., Tereshchenkova, Valeria F., Filippova, Irina Yu., Efremov, Roman G., Elpidina, Elena N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418366/
https://www.ncbi.nlm.nih.gov/pubmed/37569743
http://dx.doi.org/10.3390/ijms241512369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418366/
https://www.ncbi.nlm.nih.gov/pubmed/37569743
http://dx.doi.org/10.3390/ijms241512369

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