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Dissecting the Structural Dynamics of Authentic Cholesteryl Ester Transfer Protein for the Discovery of Potential Lead Compounds: A Theoretical Study

Current structural and functional investigations of cholesteryl ester transfer protein (CETP) inhibitor design are nearly entirely based on a fully active mutation (CETP(Mutant)) constructed for protein crystallization, limiting the study of the dynamic structural features of authentic CETP involved...

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Detalles Bibliográficos
Autores principales: Zhao, Yizhen, Hao, Dongxiao, Zhao, Yifan, Zhang, Shengli, Zhang, Lei, Yang, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418423/
https://www.ncbi.nlm.nih.gov/pubmed/37569628
http://dx.doi.org/10.3390/ijms241512252