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Dissecting the Structural Dynamics of Authentic Cholesteryl Ester Transfer Protein for the Discovery of Potential Lead Compounds: A Theoretical Study
Current structural and functional investigations of cholesteryl ester transfer protein (CETP) inhibitor design are nearly entirely based on a fully active mutation (CETP(Mutant)) constructed for protein crystallization, limiting the study of the dynamic structural features of authentic CETP involved...
Autores principales: | Zhao, Yizhen, Hao, Dongxiao, Zhao, Yifan, Zhang, Shengli, Zhang, Lei, Yang, Zhiwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418423/ https://www.ncbi.nlm.nih.gov/pubmed/37569628 http://dx.doi.org/10.3390/ijms241512252 |
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