A Comprehensive Technology Platform for the Rapid Discovery of Peptide Inhibitors against SARS-CoV-2 Pseudovirus Infection

We developed and validated a technology platform for designing and testing peptides inhibiting the infectivity of SARS-CoV-2 spike protein-based pseudoviruses. This platform integrates target evaluation, in silico inhibitor design, peptide synthesis, and efficacy screening. We generated a cyclic pep...

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Detalles Bibliográficos
Autores principales: Beeg, Marten, Baroni, Sara, Piotti, Arianna, Porta, Alessia, De Luigi, Ada, Cagnotto, Alfredo, Gobbi, Marco, Diomede, Luisa, Salmona, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418426/
https://www.ncbi.nlm.nih.gov/pubmed/37569522
http://dx.doi.org/10.3390/ijms241512146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418426/
https://www.ncbi.nlm.nih.gov/pubmed/37569522
http://dx.doi.org/10.3390/ijms241512146

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