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A Comprehensive Technology Platform for the Rapid Discovery of Peptide Inhibitors against SARS-CoV-2 Pseudovirus Infection
We developed and validated a technology platform for designing and testing peptides inhibiting the infectivity of SARS-CoV-2 spike protein-based pseudoviruses. This platform integrates target evaluation, in silico inhibitor design, peptide synthesis, and efficacy screening. We generated a cyclic pep...
Autores principales: | Beeg, Marten, Baroni, Sara, Piotti, Arianna, Porta, Alessia, De Luigi, Ada, Cagnotto, Alfredo, Gobbi, Marco, Diomede, Luisa, Salmona, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418426/ https://www.ncbi.nlm.nih.gov/pubmed/37569522 http://dx.doi.org/10.3390/ijms241512146 |
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