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CCR9/CXCR5 Co-Expressing CD4 T Cells Are Increased in Primary Sjögren’s Syndrome and Are Enriched in PD-1/ICOS-Expressing Effector T Cells

Primary Sjögren’s syndrome (pSS) is an autoimmune disease characterised by B cell hyperactivity. CXCR5+ follicular helper T cells (Tfh), CXCR5-PD-1hi peripheral helper T cells (Tph) and CCR9+ Tfh-like cells have been implicated in driving B cell hyperactivity in pSS; however, their potential overlap...

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Detalles Bibliográficos
Autores principales: Hinrichs, Anneline C., Kruize, Aike A., Lafeber, Floris P. J. G., Leavis, Helen L., van Roon, Joel A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418442/
https://www.ncbi.nlm.nih.gov/pubmed/37569326
http://dx.doi.org/10.3390/ijms241511952