Polynucleotides Suppress Inflammation and Stimulate Matrix Synthesis in an In Vitro Cell-Based Osteoarthritis Model

Osteoarthritis (OA) is characterized by degeneration of the joint cartilage, inflammation, and a change in the chondrocyte phenotype. Inflammation also promotes cell hypertrophy in human articular chondrocytes (HC-a) by activating the NF-κB pathway. Chondrocyte hypertrophy and inflammation promote e...

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Detalles Bibliográficos
Autores principales: Kuppa, Sree Samanvitha, Kim, Hyung-Keun, Kang, Ju-Yeon, Lee, Seok-Cheol, Yang, Hong-Yeol, Sankaranarayanan, Jaishree, Seon, Jong-Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418450/
https://www.ncbi.nlm.nih.gov/pubmed/37569659
http://dx.doi.org/10.3390/ijms241512282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418450/
https://www.ncbi.nlm.nih.gov/pubmed/37569659
http://dx.doi.org/10.3390/ijms241512282

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