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Predicting the Effect of Single Mutations on Protein Stability and Binding with Respect to Types of Mutations

The development of methods and algorithms to predict the effect of mutations on protein stability, protein–protein interaction, and protein–DNA/RNA binding is necessitated by the needs of protein engineering and for understanding the molecular mechanism of disease-causing variants. The vast majority...

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Detalles Bibliográficos
Autores principales: Pandey, Preeti, Panday, Shailesh Kumar, Rimal, Prawin, Ancona, Nicolas, Alexov, Emil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418460/
https://www.ncbi.nlm.nih.gov/pubmed/37569449
http://dx.doi.org/10.3390/ijms241512073