Humanized NSG Mouse Models as a Preclinical Tool for Translational Research in Inflammatory Bowel Diseases

The development of animal models reflecting the pathologies of ulcerative colitis (UC) and Crohn’s disease (CD) remains a major challenge. The NOD/SCID/IL2rγ(null) (NSG) mouse strain, which is immune-compromised, tolerates the engraftment of human peripheral blood mononuclear cells (PBMC) derived fr...

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Detalles Bibliográficos
Autores principales: Weß, Veronika, Schuster-Winkelmann, Paula, Karatekin, Yasemin Hazal, Malik, Simge, Beigel, Florian, Kühn, Florian, Gropp, Roswitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418464/
https://www.ncbi.nlm.nih.gov/pubmed/37569722
http://dx.doi.org/10.3390/ijms241512348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418464/
https://www.ncbi.nlm.nih.gov/pubmed/37569722
http://dx.doi.org/10.3390/ijms241512348

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