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Humanized NSG Mouse Models as a Preclinical Tool for Translational Research in Inflammatory Bowel Diseases
The development of animal models reflecting the pathologies of ulcerative colitis (UC) and Crohn’s disease (CD) remains a major challenge. The NOD/SCID/IL2rγ(null) (NSG) mouse strain, which is immune-compromised, tolerates the engraftment of human peripheral blood mononuclear cells (PBMC) derived fr...
Autores principales: | Weß, Veronika, Schuster-Winkelmann, Paula, Karatekin, Yasemin Hazal, Malik, Simge, Beigel, Florian, Kühn, Florian, Gropp, Roswitha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418464/ https://www.ncbi.nlm.nih.gov/pubmed/37569722 http://dx.doi.org/10.3390/ijms241512348 |
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