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Application of Quantitative Structure-Activity Relationships in the Prediction of New Compounds with Anti-Leukemic Activity

Leukemia invades the bone marrow progressively and, through unknown mechanisms, outcompetes healthy hematopoiesis. Protein arginine methyltransferases 1 (PRMT1) are found in prokaryotes and eukaryotes cells. They are necessary for a number of biological processes and have been linked to several huma...

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Detalles Bibliográficos
Autores principales: Sandoval, Cristian, Torrens, Francisco, Godoy, Karina, Reyes, Camila, Farías, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418467/
https://www.ncbi.nlm.nih.gov/pubmed/37569634
http://dx.doi.org/10.3390/ijms241512258