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Prostaglandin E2 (PGE2) and Roflumilast Involvement in IPF Progression

The ECM propagates processes in idiopathic pulmonary fibrosis (IPF), leading to progressive lung scarring. We established an IPF-conditioned matrix (IPF-CM) system as a platform for testing drug candidates. Here, we tested the involvement of a PGE2 and PDE4 inhibitor, Roflumilast, in the IPF-CM syst...

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Detalles Bibliográficos
Autores principales: Moshkovitz, Noa, Epstein Shochet, Gali, Shitrit, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418473/
https://www.ncbi.nlm.nih.gov/pubmed/37569768
http://dx.doi.org/10.3390/ijms241512393