Pictilisib-Induced Resistance Is Mediated through FOXO1-Dependent Activation of Receptor Tyrosine Kinases in Mucinous Colorectal Adenocarcinoma Cells

The phosphatidylinositol (PI3K)/AKT/mTOR axis represents an important therapeutic target to treat human cancers. A well-described downstream target of the PI3K pathway is the forkhead box O (FOXO) transcription factor family. FOXOs have been implicated in many cellular responses, including drug-indu...

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Detalles Bibliográficos
Autores principales: Kuracha, Murali R., Govindarajan, Venkatesh, Loggie, Brian W., Tobi, Martin, McVicker, Benita L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418489/
https://www.ncbi.nlm.nih.gov/pubmed/37569713
http://dx.doi.org/10.3390/ijms241512331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418489/
https://www.ncbi.nlm.nih.gov/pubmed/37569713
http://dx.doi.org/10.3390/ijms241512331

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