Binding Affinity of Trastuzumab and Pertuzumab Monoclonal Antibodies to Extracellular HER2 Domain †

The binding affinity of trastuzumab and pertuzumab to HER2 has been studied using both experimental and in silico methods. The experiments were conducted using the antibodies in their complete IgG form, as used in clinical therapy, and the extracellular domain of the HER2 protein in solution. This a...

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Detalles Bibliográficos
Autores principales: Cruz, Victor L., Souza-Egipsy, Virginia, Gion, María, Pérez-García, José, Cortes, Javier, Ramos, Javier, Vega, Juan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418494/
https://www.ncbi.nlm.nih.gov/pubmed/37569408
http://dx.doi.org/10.3390/ijms241512031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418494/
https://www.ncbi.nlm.nih.gov/pubmed/37569408
http://dx.doi.org/10.3390/ijms241512031

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