Insights into the Mechanism of Action of Antipsychotic Drugs Derived from Animal Models: Standard of Care versus Novel Targets

Therapeutic intervention for schizophrenia relies on blockade of dopamine D2 receptors in the associative striatum; however, there is little evidence for baseline overdrive of the dopamine system. Instead, the dopamine system is in a hyper-responsive state due to excessive drive by the hippocampus....

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Detalles Bibliográficos
Autores principales: Grace, Anthony A., Uliana, Daniela L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418544/
https://www.ncbi.nlm.nih.gov/pubmed/37569748
http://dx.doi.org/10.3390/ijms241512374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418544/
https://www.ncbi.nlm.nih.gov/pubmed/37569748
http://dx.doi.org/10.3390/ijms241512374

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