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Accumulation of F-actin drives brain aging and limits healthspan in Drosophila
The actin cytoskeleton is a key determinant of cell and tissue homeostasis. However, tissue-specific roles for actin dynamics in aging, notably brain aging, are not understood. Here, we show that there is an age-related increase in filamentous actin (F-actin) in Drosophila brains, which is counterac...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Journal Experts
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418561/ https://www.ncbi.nlm.nih.gov/pubmed/37577708 http://dx.doi.org/10.21203/rs.3.rs-3158290/v1 |