MethNet: a robust approach to identify regulatory hubs and their distal targets in cancer

Aberrations in the capacity of DNA/chromatin modifiers and transcription factors to bind non-coding regions can lead to changes in gene regulation and impact disease phenotypes. However, identifying distal regulatory elements and connecting them with their target genes remains challenging. Here, we...

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Detalles Bibliográficos
Autores principales: Sakellaropoulos, Theodore, Do, Catherine, Jiang, Guimei, Cova, Giulia, Meyn, Peter, Dimartino, Dacia, Ramaswami, Sitharam, Heguy, Adriana, Tsirigos, Aristotelis, Skok, Jane A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418566/
https://www.ncbi.nlm.nih.gov/pubmed/37577603
http://dx.doi.org/10.21203/rs.3.rs-3150386/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418566/
https://www.ncbi.nlm.nih.gov/pubmed/37577603
http://dx.doi.org/10.21203/rs.3.rs-3150386/v1

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