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MethNet: a robust approach to identify regulatory hubs and their distal targets in cancer
Aberrations in the capacity of DNA/chromatin modifiers and transcription factors to bind non-coding regions can lead to changes in gene regulation and impact disease phenotypes. However, identifying distal regulatory elements and connecting them with their target genes remains challenging. Here, we...
Autores principales: | Sakellaropoulos, Theodore, Do, Catherine, Jiang, Guimei, Cova, Giulia, Meyn, Peter, Dimartino, Dacia, Ramaswami, Sitharam, Heguy, Adriana, Tsirigos, Aristotelis, Skok, Jane A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418566/ https://www.ncbi.nlm.nih.gov/pubmed/37577603 http://dx.doi.org/10.21203/rs.3.rs-3150386/v1 |
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