Design, Synthesis, and Biological Evaluation of New Potential Unusual Modified Anticancer Immunomodulators for Possible Non-Teratogenic Quinazoline-Based Thalidomide Analogs

Sixteen new thalidomide analogs were synthesized. The new candidates showed potent in vitro antiproliferative activities against three human cancer cell lines, namely hepatocellular carcinoma (HepG-2), prostate cancer (PC3), and breast cancer (MCF-7). It was found that compounds XII, XIIIa, XIIIb, X...

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Detalles Bibliográficos
Autores principales: Mabrouk, Reda R., Abdallah, Abdallah E., Mahdy, Hazem A., El-Kalyoubi, Samar A., Kamal, Omar Jamal, Abdelghany, Tamer M., Zayed, Mohamed F., Alshaeri, Heba K., Alasmari, Moudi M., El-Zahabi, Mohamed Ayman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418715/
https://www.ncbi.nlm.nih.gov/pubmed/37569792
http://dx.doi.org/10.3390/ijms241512416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418715/
https://www.ncbi.nlm.nih.gov/pubmed/37569792
http://dx.doi.org/10.3390/ijms241512416

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