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Lipophilic Studies and In Silico ADME Profiling of Biologically Active 2-Aminothiazol-4(5H)-one Derivatives

Pseudothiohydantoin derivatives have a wide range of biological activities and are widely used in the development of new pharmaceuticals. Lipophilicity is a basic, but very important parameter in the design of potential drugs, as it determines solubility in lipids, nonpolar solvents, and makes it po...

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Detalles Bibliográficos
Autores principales: Redka, Małgorzata, Baumgart, Szymon, Kupczyk, Daria, Kosmalski, Tomasz, Studzińska, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418735/
https://www.ncbi.nlm.nih.gov/pubmed/37569606
http://dx.doi.org/10.3390/ijms241512230