Targeting KRAS in Colorectal Cancer: A Bench to Bedside Review

Colorectal cancer (CRC) is a heterogeneous disease with a myriad of alterations at the cellular and molecular levels. Kristen rat sarcoma (KRAS) mutations occur in up to 40% of CRCs and serve as both a prognostic and predictive biomarker. Oncogenic mutations in the KRAS protein affect cellular proli...

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Detalles Bibliográficos
Autores principales: Bteich, Fernand, Mohammadi, Mahshid, Li, Terence, Bhat, Muzaffer Ahmed, Sofianidi, Amalia, Wei, Ning, Kuang, Chaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418782/
https://www.ncbi.nlm.nih.gov/pubmed/37569406
http://dx.doi.org/10.3390/ijms241512030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418782/
https://www.ncbi.nlm.nih.gov/pubmed/37569406
http://dx.doi.org/10.3390/ijms241512030

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