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GTS-21 Enhances Regulatory T Cell Development from T Cell Receptor-Activated Human CD4(+) T Cells Exhibiting Varied Levels of CHRNA7 and CHRFAM7A Expression

Immune cells such as T cells and macrophages express α7 nicotinic acetylcholine receptors (α7 nAChRs), which contribute to the regulation of immune and inflammatory responses. Earlier findings suggest α7 nAChR activation promotes the development of regulatory T cells (Tregs) in mice. Using human CD4...

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Detalles Bibliográficos
Autores principales: Mashimo, Masato, Fujii, Takeshi, Ono, Shiro, Moriwaki, Yasuhiro, Misawa, Hidemi, Azami, Tetsushi, Kasahara, Tadashi, Kawashima, Koichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418795/
https://www.ncbi.nlm.nih.gov/pubmed/37569633
http://dx.doi.org/10.3390/ijms241512257