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Pentylenetetrazole-Induced Seizures Are Increased after Kindling, Exhibiting Vitamin-Responsive Correlations to the Post-Seizures Behavior, Amino Acids Metabolism and Key Metabolic Regulators in the Rat Brain

Epilepsy is characterized by recurrent seizures due to a perturbed balance between glutamate and GABA neurotransmission. Our goal is to reveal the molecular mechanisms of the changes upon repeated challenges of this balance, suggesting knowledge-based neuroprotection. To address this goal, a set of...

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Detalles Bibliográficos
Autores principales: Aleshin, Vasily A., Graf, Anastasia V., Artiukhov, Artem V., Ksenofontov, Alexander L., Zavileyskiy, Lev G., Maslova, Maria V., Bunik, Victoria I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418815/
https://www.ncbi.nlm.nih.gov/pubmed/37569781
http://dx.doi.org/10.3390/ijms241512405