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Investigation of Mutated in Colorectal Cancer (MCC) Gene Family Evolution History Indicates a Putative Role in Th17/Treg Differentiation

The MCC family of genes plays a role in colorectal cancer development through various immunological pathways, including the Th17/Treg axis. We have previously shown that MCC1 but not MCC2 plays a role in Treg differentiation. Our understanding of the genetic divergence patterns and evolutionary hist...

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Detalles Bibliográficos
Autores principales: Kubick, Norwin, Paszkiewicz, Justyna, Bieńkowska, Irmina, Ławiński, Michał, Horbańczuk, Jarosław Olav, Sacharczuk, Mariusz, Mickael, Michel Edwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418881/
https://www.ncbi.nlm.nih.gov/pubmed/37569317
http://dx.doi.org/10.3390/ijms241511940